Diabetes is a disease that bring the most complications (leading to the occurrence of other diseases ) the most . This is related to the continuously high blood sugar levels , resulting damage to blood vessels , nerves and other internal structures .
Complex Substance composition (consisting of sugar) in the blood vessel walls generate blood vessels thicken and then leaking. This condition affected reduction of the blood flow , particularly those headed to the skin and nerves.
Uncontrolled blood sugar levels also tend to lead levels of fatty substances in the blood increase, thus accelerating the occurrence of atherosclerosis ( accumulation of fatty plaques in blood vessels ) . Atherosclerosis is 2-6 times more common in diabetics .
This bad blood circulation through the large blood vessels ( macro ) can injure the brain , heart and blood vessels feet ( makroangiopati ) , while the small blood vessels ( micro) can injure the eyes , kidneys , nerves and skin and slow healing of wounds .
Diabetics can experience a variety of long term complications if diabetes is not managed properly. Complications that are common and deadly is heart attacks and strokes.
Damage to the eye blood vessels can affected vision problems caused by damage to the retina of the eye ( diabetic retinopathy ) . Abnormalities of kidney function can bring kidney failure , so patients must undergo dialysis ( dialysis ) .
Neurological disorders may manifest in several forms . If a Nerve abnormaly function ( mononeuropati ), then a normal arm or leg might became weak suddenly .
If the nerves leading to the hand , leg and foot were damaged ( diabetic polyneuropathy ), then the arms and legs can be felt as tingling or burning pain and weakness .
Nerve damage causes more frequent skin injury because patients can not control or reduce changes in pressure and temperature . Decreased blood flow to the skin can also affected the ulcers and all wound healing process slower. Ulcers on the feet can be extremely deep and have an infection and a long recuperation period, that under go some of the leg must be amputated .